ML350
Rear-Wheel Drive · Automatic 7-spd · Standard Sport Utility Vehicle 2WD
- MPG combined
- 20
- City / highway
- 18 / 23
- Engine
- 3.5L 6-cyl
- Fuel
- Premium
- Annual fuel cost
- $4,100
- Tailpipe CO₂
- 440 g/mi

The Mercedes-Benz ML-Class has been sold in the US from 2000 to 2015, in 16 model years covered here. The 2015 line-up has 6 trims with 15–25 MPG combined.
Rear-Wheel Drive · Automatic 7-spd · Standard Sport Utility Vehicle 2WD
4-Wheel Drive · Automatic 7-spd · Standard Sport Utility Vehicle 4WD
4-Wheel Drive · Automatic 7-spd · Standard Sport Utility Vehicle 4WD
4-Wheel Drive · Automatic 7-spd · Standard Sport Utility Vehicle 4WD
4-Wheel Drive · Automatic 7-spd · Standard Sport Utility Vehicle 4WD
Source: U.S. EPA / DOE fueleconomy.gov. Annual fuel cost is the EPA estimate for 15,000 miles a year at national average fuel and electricity prices.