IS 250
Rear-Wheel Drive · Automatic (S6) · Compact Cars
- MPG combined
- 24
- City / highway
- 21 / 30
- Engine
- 2.5L 6-cyl
- Fuel
- Premium
- Annual fuel cost
- $3,400
- Tailpipe CO₂
- 364 g/mi
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World Of EVEditorial
Lexus IS
The Lexus IS has been sold in the US from 2001 to 2026, in 26 model years covered here. The 2026 line-up has 2 trims with 22 MPG combined.
Model years
2015 IS trims (6)
IS 250 AWD
All-Wheel Drive · Automatic (S6) · Compact Cars
- MPG combined
- 23
- City / highway
- 20 / 27
- Engine
- 2.5L 6-cyl
- Fuel
- Premium
- Annual fuel cost
- $3,550
- Tailpipe CO₂
- 391 g/mi
IS 250 C
Rear-Wheel Drive · Automatic (S6) · Subcompact Cars
- MPG combined
- 24
- City / highway
- 21 / 30
- Engine
- 2.5L 6-cyl
- Fuel
- Premium
- Annual fuel cost
- $3,400
- Tailpipe CO₂
- 362 g/mi
IS 350
Rear-Wheel Drive · Automatic (S8) · Compact Cars
- MPG combined
- 22
- City / highway
- 19 / 28
- Engine
- 3.5L 6-cyl
- Fuel
- Premium
- Annual fuel cost
- $3,750
- Tailpipe CO₂
- 401 g/mi
IS 350 AWD
All-Wheel Drive · Automatic (S6) · Compact Cars
- MPG combined
- 21
- City / highway
- 19 / 26
- Engine
- 3.5L 6-cyl
- Fuel
- Premium
- Annual fuel cost
- $3,900
- Tailpipe CO₂
- 413 g/mi
IS 350 C
Rear-Wheel Drive · Automatic (S6) · Subcompact Cars
- MPG combined
- 22
- City / highway
- 19 / 27
- Engine
- 3.5L 6-cyl
- Fuel
- Premium
- Annual fuel cost
- $3,750
- Tailpipe CO₂
- 402 g/mi
Source: U.S. EPA / DOE fueleconomy.gov. Annual fuel cost is the EPA estimate for 15,000 miles a year at national average fuel and electricity prices.